active place avoidance task  (BioSignal Group)

Journal: Behavioral neuroscience

Article Title: Coordination of Hippocampal Theta and Gamma Oscillations Relative to Spatial Active Avoidance Reflects Cognitive Outcome After Febrile Status Epilepticus

doi: 10.1037/bne0000388

Figure Lengend Snippet: Active avoidance and the separation of FSE animals into learners and nonlearners. Behavioral results during active avoidance training sessions illustrating the number of entrances (A), the number of shocks (B) in the final 4 training sessions, and the proportion of time in each quadrant (C) relative to the shock zone (SZ = shock zone, CW = clockwise, OPP = opposite, CCW = counterclockwise) in the last training session. While no differences were found between FSE-L and controls, FSE-NL animals made significantly more shock zone entrances, received more shocks and spent more time clockwise to the shock zone than controls, denoting an inefficient avoidance strategy. FSE = febrile status epilepticus; FSE-L = FSE-learners; FSE-NL = FSE-nonlearners.

Article Snippet: Active Place Avoidance Behavioral Task In the active place avoidance task (Biosignal; Brooklyn, New York), animals learn to associate an unmarked region of space with a mild shock on a rotating arena.

Techniques:

Journal: Behavioral neuroscience

Article Title: Coordination of Hippocampal Theta and Gamma Oscillations Relative to Spatial Active Avoidance Reflects Cognitive Outcome After Febrile Status Epilepticus

doi: 10.1037/bne0000388

Figure Lengend Snippet: Behavioral and spatial cognitive demands during active avoidance on the rotating arena. (A) Rats tend to avoid the shock zone in arcs. These arcs can be divided into 5 phases: (1) Rats are at rest and move with the arena; (2) Rats remember that they need to run or be moved into the shock zone; (3) Rats run in the opposite direction of arena rotation, increasing sensorimotor demands (denoted by red and green gears); (4) Rats remember to stop running or enter the opposite side of the shock zone; (5) Rats return to rest; (B) Deconstruction of the 5 phases relative to speed and time noting different brain states associated with increased sensorimotor processing during the avoidance run and increased memory demands. (C) Example of behavioral performance during an active avoidance session and the corresponding avoidance arc. Left—Map of the proportion of time spent over the arena surface (64 pixel resolution) where black pixels indicate nonsampled regions and the blue to red color continuum indicates the least to most sampled locations on the arena surface; Middle—Path taken by rat (gray line) over the surface of the stable arena. The red triangle indicates the location of the shock zone in the avoidance context and the epochs where the rat would have received an electric shock are indicated by red circles; Right—Polar analysis of spatial sampling where the vector, angle and length of the black lines emanating from the plot center indicate the proportion of time spent at each angle of the arena (0–360° in 10° bins). The outside arc (thin black line) for each plot indicates the distribution of the longest vector lengths that account for at least 50% of the session duration.

Article Snippet: Active Place Avoidance Behavioral Task In the active place avoidance task (Biosignal; Brooklyn, New York), animals learn to associate an unmarked region of space with a mild shock on a rotating arena.

Techniques: Sampling, Plasmid Preparation